学硕:植物保护(090400)
研究方向
绿色农药创制;AI辅助的农药分子设计
教育背景
1. 2019年09月-2022年12月,williamhill官网,农药学,博士,导师:程家高 教授,Peter Maienfisch 教授
2. 2016年09月-2019年06月,williamhill官网,药学,硕士,导师:程家高 教授
3. 2012年09月-2016年06月,青岛科技大学,药物制剂,学士
工作经历
1. 2025年01月-至今,williamhill官网,英国威廉希尔官网,特聘副研究员,硕士生导师
2. 2023年01月-2024年12月,williamhill官网,英国威廉希尔官网,博士后,合作导师:钱旭红 教授
荣誉奖励
1. 国家资助博士后研究人员计划,2023
2. 上海市“超级博士后”激励计划,2023
3. 上海市优秀毕业生,2023
主持科研项目
1. 国家自然科学基金青年基金(22307039),2024年1月-2026年12月
2. 中国博士后科学基金面上项目(2023M731089),2023年7月-2024年12月
3. 上海市农业科技创新春蕾项目(沪农科T2024302),2024年11月-2027年10月
4. 上海市教育委员会“AI赋能科研计划”,2025年1月-2026年12月
发表论文(#为共同一作)
1. Dongxu Zhang#, Cong Zhou#, Suzhen Qi, Huihui Zhang, Xusheng Shao, Xiaoyong Xu, Jiagao Cheng, Zewen Liu, Zhong Li, Wu-Lin Yang, Discovery of novel neonicotinoids with conjugated diene enabled by cascade allylation/isomerization synthetic methodology. J. Agric. Food Chem. 2025, 73, 2784–2792.(一区TOP)
2. Cong Zhou#, Yijin Kong#, Huihui Zhang, Na Zhai, Zhong Li, Xuhong Qian, Zewen Liu*, and Jiagao Cheng* Computational modeling-oriented substructure splicing application in the identification of thiazolidine derivatives as potential low honeybee toxic neonicotinoids J. Agric. Food Chem. 2024, 72, 11968–11979. (一区TOP)
3. Liangliang Cheng#, Cong Zhou#, Qinglong Yuan, Letian Zhang, Xusheng Shao, Xiaoyong Xu, Zhong Li, Jiagao Cheng* 3D-QSAR model-oriented optimization of Pyrazole β-Ketonitrile derivatives with diphenyl ether moiety as novel potent succinate dehydrogenase inhibitors. Pest Manag. Sci., 2024, 80, 5299–5306.(一区TOP)
4. Yijin Kong#, Cong Zhou#, Du Tan, Xiaoyong Xu, Zhong Li, and Jiagao Cheng* Discovery of potential neonicotinoid insecticides by an artificial intelligence generative model and structure-based virtual screening. J. Agric. Food Chem. 2024, 72, 5145–5152.(一区TOP)
5. Cong Zhou, Guanglong Li, Sihui Wang, Zhong Li, Xuhong Qian, and Jiagao Cheng* Novel insecticidal benzo[4,5]imidazo[1,2-b]pyrazole derivatives identified through ring-closure scaffold hopping on fipronil. Chem. Biodivers. 2024, e202402148.
6. Xiaoyang Li#, Cong Zhou#, Wulin Yang, Zhong Li, and Jiagao Cheng* Novel insecticidal pyridylhydrazono derivatives identified via scaffold hopping and conformation regulation strategies. Chem. Biodivers. 2024, e202401767.
7. Xiaoyang Li#, Cong Zhou#, Lujue He, Zhiping Xu, Zhong Li, and Jiagao Cheng* Identification of potential novel insect TRPV channel modulators by homology modeling, binding mode analysis, virtual screening studies and chemical optimization. New J. Chem., 2024, 48, 12688-12696.
8. Cong Zhou, Zhong Li, Xuhong Qian, Jiagao Cheng*, and Peter Maienfisch* Novel acaricidal silico-containing pyrazolyl acrylonitrile derivatives identified through rational carbon−silicon bioisosteric replacement strategy. J. Agric. Food Chem. 2023, 71, 18239–18249.一区TOP)
9. Cong Zhou, Xujuan Sun, Wen Fu, Zhong Li, Jiagao Cheng*, and Peter Maienfisch*Rational exploration of novel SDHI fungicide through amide-β-ketonitrile bioisosteric replacement strategy. J. Agric. Food Chem. 2023, 71, 5483–5495.(一区TOP)
10. Cong Zhou, Xin Wang, Xiaocao Quan, Jiagao Cheng*, Zhong Li, and Peter Maienfisch*.Silicon-containing complex II acaricides-design, synthesis, and pharmacological optimization. J. Agric. Food Chem. 2022, 70, 11063–11074.(一区TOP)
11. Cong Zhou, Jiagao Cheng*, Ryan Beadle, Fergus G Earley, Zhong Li, Peter Maienfisch*.Design, synthesis and acaricidal activities of Cyflumetofen analogues based on carbon-silicon isosteric replacement. Bioorgan. Med. Chem. 2020, 28, 115509.
12. Ting Li#, Cong Zhou#, Nan Zheng, Hongbin Yang, Guanglin Kuang, Xusheng Shao, Zhong Li, Jiagao Cheng*. Insights into the synergistic mechanism of target resistance: A case study of N. lugens RDL-GABA receptors and fipronil. Biophys. Chem.2020, 265, 106426.
申请专利
1. (中国发明专利授权)程家高,Peter Maienfsch,周聪,李忠,邵旭升,徐晓勇,钱旭红. 含硅酰基乙腈化合物及其制备方法与应用. 专利号 ZL 201910415131.9. 授权日:2021-02-09
2. (中国发明专利授权)程家高,Peter Maienfsch,周聪,李忠,邵旭升,徐晓勇,钱旭红. 硅丙烯腈类化合物及其制备方法与应用. 专利号 ZL 202011460379.6. 授权日:2024-10-25
3. (国际发明专利公开)程家高,Peter Maienfsch,周聪,李忠,邵旭升,徐晓勇,钱旭红. 硅丙烯腈类化合物及其制备方法与应用. 公开号 WO 2022121908 A1. 公开日2022-06-16
4. (中国发明专利公开)程家高,周聪,Peter Maienfsch,李忠,邵旭升,徐晓勇,钱旭红. 酮腈类化合物及其制备方法与应用. 公开号 CN 117658935 A. 公开日2024-03-08.
5. (中国发明专利公开)程家高,程亮亮,周聪,李忠,邵旭升,徐晓勇,钱旭红. 一种长链酮腈类化合物及其制备方法与应用. 公开号 CN 119462506 A 公布日2025-02-18
6. (中国发明专利申请)程家高,周聪,李晓阳,王丛,吴彪,孙绪娟,李忠,邵旭升,徐晓勇,钱旭红. 一种硫酯类化合物及其制备方法与应用. 申请号:202510087352.3